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Home > Health & Fitness > Healthwise > Vasodilators for Mitral Valve Regurgitation
Vasodilators work on different substances
in the body to help widen (dilate) blood vessels.
These medicines might help mitral valve regurgitation because the wider
blood vessel reduces resistance in blood flow and makes it easier for blood
to move forward from the left atrium to the left ventricle to the aorta. This
helps reduce the amount of blood that leaks backward through the valve into the
Vasodilators are used to treat acute mitral valve regurgitation in the hospital. For chronic regurgitation, they might be used if you have symptoms or high blood pressure, or if your heart is not pumping blood as well as normal.
Vasodilators can reduce the severity of mitral valve regurgitation when the left ventricle is not working as well as normal.1
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
Call 911 or other emergency services right away if you have:
Call your doctor if you have:
Common side effects of this medicine include:
Nitroprusside is generally only used for acute
mitral regurgitation in the hospital. If nitroprusside is used, you are closely watched, because this medicine may cause severe low blood pressure.
Reference for a full list of side effects. (Drug Reference is not available in
A cough is one of the most
common side effects of ACE inhibitors. But most people do not get a cough. The cough tends to be a minor
problem for most people who have it. They feel that they can live with it in exchange for the benefits of this medicine.
If you take an ACE inhibitor and have a problem with coughing, talk with your doctor. Your cough may be caused by something else, like a cold. Do not stop taking your medicine unless your doctor tells you to.
If you have a cough that is a problem for you, then your doctor might give you an angiotensin II receptor blocker (ARB) instead. ARBs are less likely to
cause a cough.
ACE inhibitors may interact with other medicines
nonsteroidal anti-inflammatory drugs (NSAIDs),
antacids, potassium supplements, certain diuretics, and lithium. If you are
taking one of these medicines, talk with your doctor before you take an ACE
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Do not use ACE inhibitors if you are pregnant, breast-feeding, or planning to get pregnant. If you need to use this medicine, talk to your doctor about how you can prevent pregnancy.
If you take an ACE inhibitor, your doctor may check your potassium levels and how your kidneys are working to make sure this medicine is not causing problems.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Bonow RO, et al. (2008). 2008 Focused update
incorporated into the ACC/AHA 2006 Guidelines for the management of patients
with valvular heart disease: A report of the American College of
Cardiology/American Heart Association Task Force on Practice Guidelines
(Writing committee to revise the 1998 Guidelines for the management of patients
with valvular heart disease). Circulation, 118(15):
Current as of:
March 12, 2014
Rakesh K. Pai, MD, FACC - Cardiology, Electrophysiology & John A. McPherson, MD, FACC, FSCAI - Cardiology
How this information was developed to help you make better health decisions.
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