Skip to Content
Wild yam and progesterone creams are available without a prescription
and are marketed for relieving
Wild yam. Although wild yam cream is marketed
as a source of natural progesterone, it does not contain progesterone, and the
body cannot convert it into progesterone.footnote 1
Progesterone creams. Some women use "natural"
progesterone creams to correct low progesterone levels. Research is mixed about
whether the cream is absorbed into the body.
You can't actually know how much progesterone you are getting
without having a whole-blood progesterone test. Because of this and the
following concerns, some experts are concerned about use of over-the-counter
progesterone cream.footnote 2
American College of Obstetricians and Gynecologists (2001, reaffirmed 2010). Use of botanicals for management of menopausal symptoms. ACOG Practice Bulletin No. 28. Obstetrics and Gynecology, 97(6, Suppl): 1–11.
Hermann AC, et al. (2005). Over-the-counter progesterone cream produces significant drug exposure compared to a Food and Drug Administration-approved oral progesterone product. Journal of Clinical Pharmacology, 45(6): 614–619.
ByHealthwise StaffPrimary Medical ReviewerAnne C. Poinier, MD - Internal MedicineSpecialist Medical ReviewerCarla J. Herman, MD, MPH - Geriatric Medicine
Current as ofFebruary 25, 2016
Current as of:
February 25, 2016
Anne C. Poinier, MD - Internal Medicine & Carla J. Herman, MD, MPH - Geriatric Medicine
To learn more about Healthwise, visit Healthwise.org.
© 1995-2016 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
© Copyright 2017 Rush-Copley Medical Center • 2000 Ogden Avenue; Aurora, IL 60504
Main: 630-978-6200 • Physician Referral & Information: 630-978-6700 or 866-4COPLEY (866-426-7539)