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Corpus callosotomy is a type of surgery that disconnects the
two sides (hemispheres) of the brain. It is used most often on children with
Lennox-Gastaut syndrome, a severe form of epilepsy that causes frequent
seizures and intellectual disability and does not respond well to drug therapy.
Corpus callosotomy is not a cure for epilepsy. But it prevents generalized
seizures in most of those who have the surgery. Partial seizures do not respond
as well to this type of surgery. Partial seizures may actually get worse after
Current as of:
February 20, 2015
John Pope, MD - Pediatrics & Steven C. Schachter, MD - Neurology
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