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Scleroderma is a rare disease in which a person's immune system
begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result,
connective tissue of the skin, lungs, and internal organs—especially the
esophagus, kidneys, and digestive tract—is replaced with scar tissue. This
change causes the tissues to become stiff and the muscles to not work as
In the esophagus, this makes it:
CREST syndrome is a limited type of scleroderma that can also affect the esophagus.
ByHealthwise StaffPrimary Medical ReviewerAdam Husney, MD - Family MedicineMartin J. Gabica, MD - Family MedicineKathleen Romito, MD - Family MedicineSpecialist Medical ReviewerPeter J. Kahrilas, MD - Gastroenterology
Current as ofOctober 31, 2016
Current as of:
October 31, 2016
Adam Husney, MD - Family Medicine & Martin J. Gabica, MD - Family Medicine & Kathleen Romito, MD - Family Medicine & Peter J. Kahrilas, MD - Gastroenterology
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